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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4
All Species:
3.64
Human Site:
T12
Identified Species:
5.33
UniProt:
O43172
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43172
NP_004688.2
522
58449
T12
R
A
S
S
T
Q
A
T
K
T
K
A
P
D
D
Chimpanzee
Pan troglodytes
XP_520198
559
62217
T49
S
R
A
S
S
T
A
T
K
T
K
A
P
D
D
Rhesus Macaque
Macaca mulatta
XP_001102859
521
58408
K12
R
T
S
S
T
A
T
K
T
K
T
P
D
D
L
Dog
Lupus familis
XP_532038
521
58332
K12
R
A
A
S
T
A
T
K
T
K
A
P
D
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAW6
521
58352
K12
R
A
S
S
T
T
T
K
T
K
A
P
D
D
L
Rat
Rattus norvegicus
Q5BK30
415
45841
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518220
390
43930
Chicken
Gallus gallus
Q5ZMA2
505
55116
P12
C
S
I
S
N
E
V
P
E
H
P
C
V
S
P
Frog
Xenopus laevis
Q5FWQ6
415
45899
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
Honey Bee
Apis mellifera
XP_393186
525
59172
K12
E
D
L
V
Y
V
K
K
Q
K
T
V
H
Y
G
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
G9
S
F
V
C
G
I
S
G
E
L
T
E
D
P
V
Sea Urchin
Strong. purpuratus
XP_795434
502
56264
K12
D
G
L
S
A
L
K
K
P
R
V
H
Y
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22212
554
61823
L23
Q
I
S
A
P
P
V
L
Q
D
A
S
S
L
P
Baker's Yeast
Sacchar. cerevisiae
P20053
465
52424
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99
99.2
N.A.
98.8
25.4
N.A.
71.2
21
24.1
24.3
N.A.
22.2
58.2
22
62
Protein Similarity:
100
93.1
99.2
99.6
N.A.
99.4
40.6
N.A.
73.3
41.3
41.3
41.5
N.A.
39.6
72.9
40.6
77
P-Site Identity:
100
66.6
33.3
33.3
N.A.
40
0
N.A.
0
6.6
0
0
N.A.
0
0
0
6.6
P-Site Similarity:
100
80
33.3
40
N.A.
40
0
N.A.
0
26.6
0
0
N.A.
0
6.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.7
51.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
13
7
7
13
13
0
0
0
19
13
0
0
0
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
0
0
7
0
0
25
32
13
% D
% Glu:
7
0
0
0
0
7
0
0
13
0
0
7
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
7
0
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
0
% H
% Ile:
0
7
7
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
32
13
25
13
0
0
0
0
% K
% Leu:
0
0
13
0
0
7
0
7
0
7
0
0
0
7
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
7
0
7
7
0
7
19
13
7
13
% P
% Gln:
7
0
0
0
0
7
0
0
13
0
0
0
0
0
0
% Q
% Arg:
25
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
13
7
25
44
7
0
7
0
0
0
0
7
7
7
0
% S
% Thr:
0
7
0
0
25
13
19
13
19
13
19
0
0
0
7
% T
% Val:
0
0
7
7
0
7
13
0
0
0
7
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _